Filaggrin anticorps (AA 998-1104)

N° du produit ABIN6294618

Cet anticorps anti-Filaggrin est un anticorps Souris Monoclonal détectant Filaggrin dans IHC, IF et FACS. Adapté pour Humain.

Aperçu rapide pour Filaggrin anticorps (AA 998-1104) (ABIN6294618)

Antigène: Filaggrin (FLG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Filaggrin est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-Filaggrin anticorps

Épitope: AA 998-1104

Fonction: Mouse anti-Human Filaggrin Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.

Immunogène: Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Filaggrin

Antigène: Filaggrin (FLG)

Autre désignation: Filaggrin

Sujet:

Target Description: Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

Gene Symbol: FLG

ID gène: 2312

UniProt: P20930

Pathways: Sensory Perception of Sound, Stem Cell Maintenance